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Omega-3 Fatty Acid Supplementation Reduces Inflammation, Pain, and Joint Damage in Osteoarthritis

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QUOTE BOARD

"Osteoarthritis (OA) is a degenerative joint disease characterized by the destruction of the articular cartilage, resulting in a pro-inflammatory response."

"Treatment for osteoarthritis remains inconsistent due to the inability to determine the underlying mechanism of disease onset, severity of symptoms, and complicating comorbidities. In recent years, diet and nutritional supplements have gained interest regarding slowing the disease process, prevention, and treatment of OA. This is due to their anti-inflammatory [inflammation resolving] properties, which result in a positive influence on pain, joint mobility, and cartilage formation."

"Omega-3 PUFA produces an anti-inflammatory effect, altering the function of vascular and carcinogen [cancer causing] biomarkers, including metabolic diseases, chronic inflammation, and conditions that lead to a frail musculoskeletal system."

WHAT YOU NEED TO KNOW

"Over the years, pharmacological treatments have been assessed to treat symptoms of osteoarthritis, yet with variable success. Through suppression of COX and PGEs, NSAIDs are often used, yet with limited symptom improvement and frequently reported side effects. Acetaminophen and opioids have been prescribed; however, there is always the question of whether the risk of an unfavorable response outweighs the advantage of potential pain control."

"Omega-3 polyunsaturated fatty acids (PUFA) have demonstrated an influential role in the progression of OA, resulting in the reduction of cartilage destruction, inhibition of pro-inflammatory cytokine cascades, and production of oxylipins that promote anti-inflammatory [inflammation resolution] pathways."

WHAT YOU NEED TO DO

You need to supplement with a sufficient daily dose of Omega-3 fatty acids and, as you have read in a multitude of previous newsletters, a sufficient daily dose of Vitamin D which is also a potent resolver of hyper-inflammation. This is exactly why Dr. Chestnut formulated OmegA+D Sufficiency™ with sufficient daily amounts of omega-3, vitamin D, and very importantly, a synergistic amount of Vitamin A from cod liver oil (Vitamin A and D work synergistically together and upregulate the receptors of each other).

For more information and to order OmegA+D Sufficiency™ and the other Innate Choice® Essential Nutrient System Supplements please visit www.eatwellmovewellthinkwell.com.

Reference:

Shawl et al. (2024) Omega-3 Supplementation and Its Effect on Osteoarthritis. Nutrients 2024,16, 1650. https://doi.org/10.3390/nu16111650

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